Protein Modification Reagents
ILEX LIFE SCIENCES LLC 3-D LIFE PEG-LINK 3 X 200 UL
3-D Life PEG-Link, non-cell-degradable thiol-modified polyethylene glycol, hydrogel crosslinker component (3 x 200 ul). INTRO: 3-D Life technology, manufactured in Germany by Cellendes GmbH, is an integrated system for generation of hydrogels used in 3D cell culture. 3-D Life represents the most flexible system for biomimetic hydrogel design. DESCRIPTION: 3-D Life PEG-Link consists of polyethylene glycol carrying a thiol at each end. When combined with the 3-D Life Hydrogel polymers, thiol groups on PEG-Link form stable thioether bonds with the thiol-reactive groups on the polymers, resulting in formation of the hydrogel. PEG-Link can be used with 3-D Life functionalized polymers Mal-PVA, Mal-Dextran, SG-PVA and SG-Dextran. APPLICATION: 3-D Life PEG-Link is used together with thiol-reactive polymers of the 3-D Life system to establish 3-D cell cultures. QUANTITY: When used with polymers of the 3-D Life Hydrogel system up to 6 ml hydrogel can be generated, depending on gel stiffness.
eMolecules Mal-PEG4-Val-Cit-PAB-PNP | 2112738-09-5 | MFCD30828694 | 96.2% | 50 MG
Mal-PEG4-Val-Cit-PAB-PNP | 2112738-09-5 | MFCD30828694 | 96.2% | 50 MG
eMolecules Amino-PEG12 | 933789-97-0 | 1G | Purity: 98%
Broadpharm | Amino-PEG12 | 1G | 933789-97-0 | MFCD18434416 | MW:515.259
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Medchemexpress LLC Azido-PEG5-CH2CO2H | 217180-81-9 | MFCD31561141 | 98.9% | 321.33 g/mol | C12H23N3O7 | 25 MG
Azido-PEG5-CH2CO2H is an azide-functional polyethylene glycol (PEG) linker containing five ethylene glycol units, used as a cleavable spacer for bioconjugation. It is commonly applied in antibody-drug conjugate and PROTAC linker synthesis, and as a reagent for click chemistry (CuAAC and SPAAC).
- Azide-functional group for click chemistry (CuAAC and SPAAC).
- Five-unit PEG spacer provides hydrophilicity and flexibility.
- Cleavable carboxylic acid terminus suitable for conjugation strategies.
- High reported purity (~98.9%).
- Molecular weight ~321.33 g/mol; formula C12H23N3O7.
- Available in small research quantities (e.g., 25 mg).
Medchemexpress LLC Biotin-PEG5-amine | 113072-75-6 | 96.24% | C22H42N4O7S | 100 MG
Biotin-PEG5-amine is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Biotin-labeled, PEG-based linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
Medchemexpress LLC Mal-amido-PEG2-NHS ester | 955094-26-5 | MFCD11041137 | 99.3%
Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester The NHS ester can be used to label the primary amines (-NH2) of proteins amine-modified oligonucleotides and other amine-containing molecules[1][2]
STA PHARMACEUTICAL US LLC Fmoc-NH-PEG6-CH2CH2COOH | 5 g | CAS 882847-34-9 | MDL MFCD06656474
Fmoc-NH-PEG6-CH2CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 882847-34-9
- MDL: MFCD06656474
- InChIKey: HEGZERUHBVYZPH-UHFFFAOYSA-N
- Molecular Weight: 575.655
- Molecular Formula: C30H41NO10
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
Cayman Chemical VH 032 LInker 2 5mg
A VHL Ligand 1 derivative; comprises the VHL ligand domain and PEG linker of the BET inhibitor-containing PROTACs MZ2 and MZP-55
Medchemexpress LLC 1,11-Bis(methanesulfonyloxy)-3,6,9-trioxandecane | 55400-73-2 | 95.0% | 350.41 | 1 G
Ms-PEG4-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
![eMolecules Broadpharm / DSPE-PEG-IA MW 2000 / 100mg / 649282255 / BP-26258 / 90.000 / / [null] / 1003.091 / C46H88IN2O11P](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502475556.JPG-250.jpg)
eMolecules Broadpharm / DSPE-PEG-IA MW 2000 / 100mg / 649282255 / BP-26258 / 90.000 / / [null] / 1003.091 / C46H88IN2O11P
Broadpharm / DSPE-PEG-IA MW 2000 / 100mg / 649282255 / BP-26258 / 90.000 / / [null] / 1003.091 / C46H88IN2O11P
eMolecules TBDMS-PEG5-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite | 1807521-08-9 | MFCD28142479 | 500mg
Broadpharm | TBDMS-PEG5-1-O-(b-cyanoethyl-N,N-diisopropyl)phosphoramidite | 500mg | 550804124 | BP-22319 | 0.000 | 1807521-08-9 | MFCD28142479 | 508.712 | C23H49N2O6PSi
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Medchemexpress LLC Cy5-PEG3-endo-BCN | 1881221-50-6 | 98.4% | 869.57 | 1 MG
Cy5-PEG3-endo-BCN is a dye derivative of Cyanine 5 (Cy5) that incorporates three PEG units. It features the lyophilic bidentate macrocyclic ligand endo-BCN, which allows for the synthesis of additional macrocyclic complexes. In click chemistry applications, endo-BCN can react with azide-containing molecules to form stable triazoles without the need for catalysts.
- Dye derivative of Cyanine 5.
- Contains 3 PEG units.
- Includes the lyophilic bidentate macrocyclic ligand endo-BCN.
- Suitable for synthesizing macrocyclic complexes.
- Reacts with azide groups in click chemistry to form stable triazoles, even in the absence of catalysts.
eMolecules Fmoc-N-amido-PEG6-acid | Broadpharm | 882847-34-9 | MFCD06656474 | 575.655 | C30H41NO10 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 100mg | 208939966
Fmoc-N-amido-PEG6-acid | Broadpharm | 882847-34-9 | MFCD06656474 | 575.655 | C30H41NO10 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCNC(=O)OCC1c2ccccc2-c2ccccc12 | 100mg | 208939966
eMolecules Hydroxy-PEG3-SS-PEG3-alcohol | 5662-81-7 | MFCD28976684 | 500mg
Broadpharm | Hydroxy-PEG3-SS-PEG3-alcohol | 500mg | 550804247 | BP-22830 | 98.000 | 5662-81-7 | MFCD28976684 | 418.560 | C16H34O8S2
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Medchemexpress LLC Bis-Mal-Lysine-PEG4-TFP ester | 1426164-53-5 | 98.0% | C37H45F4N5O13 | 25 MG
Bis-Mal-Lysine-PEG4-TFP ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These molecules connect a ligand for an E3 ubiquitin ligase with a ligand for a target protein, enabling the selective degradation of target proteins through the intracellular ubiquitin-proteasome system. It is intended for research use only. For optimal stability, store at 4°C, protected from light. When in solvent, store at -80°C for 6 months or -20°C for 1 month, also protected from light.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system for selective protein degradation
- Highly soluble in DMSO (100 mg/mL)
- Demonstrates good solubility in various in vivo protocols